Lactobacillus sporogenes

Lactic acid bacillus / Bacillus coagulans

Lactobacilli are helpful type of bacteria naturally occuring in the intestines and constitute a major part of intestinal flora. Lactobacillus sporogenes plays a very important role in upkeep of health and is responsible for the synthsis of B-complex factors. Vitamin K, digestive enzymes required in digestion of various carbohydrates, fat and protein foods and their absorption into body.

Lactobacillus sporogenes has many interesting properties, the most notable of which is its ability to transform into small oval bodies known as spores. The spores are extremely stable, have a long life and are resistant to high temperature, gastric acid and bile acid.

In the host these spores survive gastric acidity, germinate in the duodenum, proliferate in the small intesine producing abundant lactic acid to prevent proliferation of harmful putrefactive bacteria and create an environment for normal conditioning of the gastrointestinal tract, where as the performance of non-spore forming (vegetative cells) Lactobacilli has always been a question mark because of their fragility in the harsh intestinal conditions.

Lactobacillus sporogenes does not consume vitamins during its proliferation or growth. It also produces biologically active L (+) Lactic acid, which is completely metabolised leading to glycogen synthesis and ideally, fulfils WHO recommendation for products of infant nutrition programs. Currently, Lactobacillus sporogenes formulations are used for various indications like diarrohea (neonatal, infant, adult and antibiotic induced ), constipation, lactose intolerance, candidiasis, dyspepsia, colits etc.In fact beyond its well-established usefulness in promoting digestive health, its most impressive research finding is in the area of containing cholesterol levels. Lactobacillus sporogenes has been documented to significantly lower total serun cholesterol & the LDL-cholesterol to HDL-cholesterol ratio without any side effects in hypercholesterolaemia.

Lactobacillus spores are capable of providing protection from pathogenic invasions into intestinal tract and help to restore the normal balance of the intestinal flora after antimicrobial drugs treatment. Thus, they possess ideal and desired characteristics of drug that does not cause any pathological or pharmacological side effects.